CD276 and neoplasm: Target: B7-H3Expression: all human NB cell lines tested expressed B7-H3; Not expressed in the murine NB cell lines, NX-S2 and Neuro2aIn vitro: NB cells and multicellular tumor spheroids models were treated with escalating concentrations (40-80-160-320-640 ng/mL)In vivo: 1 mg/kg vobra duo administered intravenously one time a week for 3 weeks (QWx3); in the resected mouse NB models the regimen was QWx4