Target: GD2Expression: expressed in all the cell lines under investigationIn vitro: evaluation of the tracer binding affinities (Kd) for anti-GD2 and DTPA-aGD2-IR800 were 2.39 nM (0.99-4.62 nM, 95% CI) and 21.31 nM (14.06-32.16 nM, 95% CI)In vivo: injection of the SK-N-BE(2) human-derived NB in the left adrenal gland of the mice; tracer detection 3 and 4 days later a tail vein injections of 111In-αGD2-IR800 (4.8 MBq/50 μg in 100 μl DPBS) in mice bearing NB xenograft. Here, MIR4435-2HG is linked to neuroblastoma.