In the future, CXCL10 and CXCL11 knockout mice may be used to further verify the mechanism of CXCL10 and CXCL11 in tumor immune cell infiltration of pancreatic cancer, so as to further study the maintenance or restoration of tumor infiltration efficiency of CD8+ T cells and assist the development of tumor-specific CTLs in lymphoid organs. The gene discussed is CD8A; the disease is pancreatic neoplasm.