Although there are relatively few studies directly targeting the association between nasopharyngeal carcinoma and SRSF, it has been demonstrated that SRSF1-mediated circPVT1 maturation processing positive feedback regulates circPVT1 expression in nasopharyngeal carcinoma, which provides a candidate molecular marker and a potential therapeutic target for the diagnosis of metastatic nasopharyngeal carcinoma. Here, SRSF1 is linked to nasopharyngeal carcinoma.