Similarly, SRSF3 affected the proliferation, migration, and survival of CRC cells through the ArhGAP30/Ace-p53 signaling pathway; SRSF9 upregulated EEF1D (eukaryotic translation elongation factor 1D) to promote CRC proliferation and metastasis (Wang J. L. et al., 2020; Wang et al., 2024). The gene discussed is ACE; the disease is colorectal carcinoma.