Endothelial cells can secrete CXCL10, contributing to the progression of disorders such as retinal ischemia‒reperfusion, Alzheimer's disease, multiple sclerosis, and neuronal injury (Tokunaga et al. 2018); it binds to the CXCR3 receptor and can regulate the immune response by activating and attracting leukocytes (Lee et al. 2009). The gene discussed is CXCL10; the disease is retinal ischemia.