CXCL10 and early-onset autosomal dominant Alzheimer disease: Endothelial cells can secrete CXCL10, contributing to the progression of disorders such as retinal ischemia‒reperfusion, Alzheimer's disease, multiple sclerosis, and neuronal injury (Tokunaga et al. 2018); it binds to the CXCR3 receptor and can regulate the immune response by activating and attracting leukocytes (Lee et al. 2009).