SERPINE1 and polycystic ovary syndrome: Notably, PAI‐1 expression was fluid throughout the beginning of the cycle, increasing at the same time and rate as the control group, thought to be a necessary step; however, as the cycle progresses and the control group begins to taper the expression of PAI‐1, its concentration continues to increase in PCOS model mice, supporting PAI‐1's implication in PCOS [63] (Figure 4).