Moreover, pTBK1 levels were not increased in PARP7 KO EO771 mouse mammary cancer cells upon induction of the IFN-I signaling with the STING agonist dimethylxanthenone acetic acid (DMXAA) and PARP7 inhibition did not increase pTBK1 levels in wild-type cells treated with DMXAA (Rasmussen et al, 2023). This evidence concerns the gene TIPARP and breast cancer.