TMPRSS2 and androgenetic alopecia: In addition to the research trends identified in our top-cited articles, it is important to consider emerging evidence that suggests a potential causational link between androgenetic alopecia and COVID-19 severity.[45] Studies have suggested that AGA may predispose patients to more severe SARS-CoV-2 infection via an androgen mediated pathway.[46] Specifically, transmembrane protease serine 2 is activated by androgens and has been posited to help mediate the entrance of COVID-19 into cells through the ACE-2 receptor.