AFP and intrahepatic cholangiocarcinoma: Older age (OR = 1.04, P = .041), biliary diseases (OR = 5.1, P < .001), elevated CA19-9 (OR = 4.35, P < .001), CEA (OR = 1.25, P = .048), WBC (OR = 1.5, P = .005), neutrophil ratio (OR = 1.28, P = .022), monocyte count (OR = 2.1, P < .001), monocyte ratio (OR = 1.72, P < .001), and NLR (OR = 1.45, P = .003) increased ICC risk, while HBV history (OR = 0.68, P = .012), elevated AFP (OR = 0.36, P < .001), and LMR (OR = 0.7, P = .003) were protective.