ADGRG1 and acute myeloid leukemia: Assay for transposase-accessible chromatin in acute myeloid leukemia samples revealed that high ADGRG1 level correlated with both WNT and Hedgehog signal partway activity and that ADGRG1 suppression led to downregulation, at the RNA level, of “WNT-related” genes, including DVL1 (79).