The most common carrier genes detected were not KSD-associated, including susceptibility to end stage renal disease (APOL1, N = 16), congenital nephrotic syndrome type 2 (NPHS2, N = 6), sickle cell disease (HBB, N = 3), and methylmalonic aciduria (MUT, N = 3). The gene discussed is APOL1; the disease is stage 5 chronic kidney disease.