Given the single nucleotide polymorphism (SNP) site rs7216389 at ORMDL3 locus is associated with the susceptibility of childhood asthma (Moffatt et al., 2007) and virus-induced respiratory wheezing illnesses (Calışkan et al., 2013), we took the genotype of this SNP into account. Here, ORMDL3 is linked to childhood onset asthma.