Previous studies have shown that tumor cells in TGCT derive from Fbs.[27, 28] A recent study has indicated the potential of GFPT2 as a marker for tumor cells in TGCT and its association with activation of the Hippo signaling pathway.[29] Consistent with those findings, we discovered that the above‐described Fb subpopulation indeed expressed higher levels of GFPT2 (Figure S3D, Supporting Information) and scored higher on activation of the Hippo pathway (Figure S3E, Supporting Information) than other Fb subpopulations. Here, GFPT2 is linked to neoplasm.