CD8B and diffuse large B-cell lymphoma: It has been described that exogenous overexpression of CircCFL1 (by plasmid transfection) in DLBCL cell lines OCI-Ly7 and OCI-Ly3 resulted in the upregulation of p-AKT, thus, CircCFL1 activated the AKT pathway and promoted the proliferation of DLBCL cells.