HAMP and Iron deficiency anemia: The management of chronic anemia in patients with advanced CKD may become particularly complex when superimposed with SARS-CoV-2 infection; indeed, the acute inflammatory response enhanced by viral infection can exacerbate functional iron deficiency and the inadequate utilization of iron stores, decrease iron absorption through enhanced hepcidin production, suppress EPO production, direct viral bone marrow invasion, and activate autoimmune cascades against red blood cells [13,14,15].