MKNK2 and cancer: For instance, SRSF1 regulates the splicing of genes, such as cyclin D1, MNK2, and RON1,[37, 38, 39] while SRSF2, SRSF4, SRSF5, and SRSF6 are involved in the splicing of apoptosis‐related genes.[40, 41, 42, 43] SRSF6 predominantly controls the splicing of EMT‐related genes.[44] Therefore, the variations in CLK4 and SRSF protein expression levels in cancer cells, along with the differences in the chemical structure and selectivity of the compounds, lead to diverse inhibitory responses among SRSFs.