The previous study proved that tumor cells could specifically produce unique Collagen I homotrimers, thereby promoting pancreatic cancer progression.[41] Consistent with this result, knockdown of COL1A1 may result in a reduction in the production and trimerization of COL1A1 using non‐denaturing gel electrophoresis and Western blot (Figure S9, Supporting Information). The gene discussed is COL1A1; the disease is pancreatic neoplasm.