FIS1 and ischemia: P110 is an inhibitor designed to target the interaction between Drp1 and Fis1, mitigating pathological mitochondrial structure and functionality in various models, including neurodegeneration, ischemia, and sepsis.[46] In this study, P110 was used to inhibit the activation of the Drp1‐Fis1 pathway and protect cells from mitochondrial damage in diabetic conditions.