Indeed, dietary methionine restriction diminishes the YTH domain‐containing family protein 1 (YTHDF1)‐mediated N6‐methyladenosine (m6A) methylation and translation of immune checkpoints, including PD‐L1 and V‐domain Ig suppressor of T cell activation (VISTA),[29] and boosts cyclic GMP‐AMP synthase (cGAS) activity by blocking SUV39H1‐mediated cGAS methylation,[30] in tumor cells, thus alleviating tumor progression. This evidence concerns the gene VSIR and neoplasm.