In addition to increased pmel-17 CD8+ infiltration into the tumor (Supplemental Figure 1, A–C; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.182563DS1), Fgl2–/– mice exhibited decreased tumor size and weight compared with WT B16 tumor–bearing mice (Supplemental Figure 1, D and E). This evidence concerns the gene CD8A and neoplasm.