On the other hand, AR signaling pathway involves various mediators regulated by lncRNA using various mechanisms, for example, Prostate cancer antigen 3 (PCA3) modulates PCa cell survival via modulating the AR signaling and is now used in PCa diagnosis [15], SChLAP1 (second chromosome locus associated with prostate-1) was identified as a highly prognostic lncRNA that differentially expressed in aggressive and indolent form of PCa [16]. Here, PCA3 is linked to posterior cortical atrophy.