Effects of RBM3 increasing (abbreviations: ASO, antisense oligonucleotide; HD, Huntington disease; hNSCs, human neural stem cells; i.c.v., intracerebroventricular; i.p., intraperitoneal; MPP+, 1-methyl-4-phenylpyridinium; NSCs, neural stem cells; OBSC, organotypic brain slice culture; OGD, oxygen and glucose deprivation; PC12, rat pheochromocytoma cells; PD, Parkinson disease; ROT, rotenone; SGZ, subgranular zone; SNP, Sodium nitroprusside; STS, staurosporine; SVZ, subventricular zone; tMCAO, transient middle cerebral artery occlusion; i.c., intracerebral). The gene discussed is RBM3; the disease is Huntington disease.