However, age, BMI, smoking, alcohol consumption, aspirin use, intestinal polyps, diabetes, hypertension, carotid atherosclerosis, chronic obstructive pulmonary disease (COPD), gut microbiota dysbiosis, fatty liver, Plt, ALT, AST/ALT ratio, TBil, IBiL, TBA, CEA, TC, and HDL-C showed statistically significant differences between the CRC group and control group (p < 0.05) (Table 1). The gene discussed is CEACAM5; the disease is Hypertension.