More ATF5 was localized in the nuclei of pancreatic cancer cells (KP4, AsPC1, and SUIT2) and lung cancer cells (A549) cultured on stiff ECMs (collagen-coated glass dishes) than that in those cultured on soft ECMs (collagen gels); (Figures 1B and 1C). This evidence concerns the gene ATF5 and familial pancreatic carcinoma.