AAU was also associated with the proliferation of CD4 and CD8 subtypes in the PBMCs, which correlates with an increase in CD4 and CD8 populations in the aqueous humor and PBMCs in various types of human uveitis (19) and correlates with a recent study reporting the expansion of CD8 clones restricted to certain autoantigens presented by HLA-B27 (52). This evidence concerns the gene CD8A and uveitis.