In control 0g compared to control 1g, Interferon alpha-inducible protein 27 (IFI27) and Annexin A1 (ANXA1), typically overexpressed during EMT in cancers [132,133] were downregulated (log2 fold changes of −1.458 and −1.174, respectively), suggesting that microgravity may reverse EMT in free-floating spheroids, as shown by previous studies [107]. This evidence concerns the gene IFI27 and cancer.