Additionally, under 7 %0g compared to 7 %1g, Keratin 8, 18, and 19 (KRT8, KRT18, KRT19), which are usually underexpressed during EMT in cancers [[134], [135], [136]], were also downregulated (log2 fold changes of −2.504, −1.732, and −2.072, respectively), indicating that the stiff ECM's effect on EMT was negated under microgravity conditions. Here, KRT18 is linked to cancer.