We then constructed a tumor metastasis model that MHCC97H or HCCLM3 stably expressing firefly luciferase with RAC3 stable overexpression or silencing was injected via the tail vein into NCG (NOD/ShiLtJGpt‐Prkdcem26Cd52Il2rgem26Cd22/Gpt) mice. The gene discussed is RAC3; the disease is neoplasm.