RAC3 and hepatocellular carcinoma: We found that PRKACB (key molecule in cAMP signaling), p‐ERK/ERK (key molecules in MAPK signaling), and Rap1b (key molecule in Rap1 signaling) were upregulated through RAC3 overexpression in HCC cells, which could be inhibited by NNMT knockdown (Figure 5L).