Reduction in antioxidant glutathione (GSTP1 identified here) may occur in MSA [23, 57], but peroxiredoxins or CBR1 (both proteins protect from oxidative stress) have not been directly implicated in MSA but have been implicated in other neurodegenerative diseases and neurotoxic insults [21, 31]. Here, GSTP1 is linked to multiple system atrophy.