Consistently, we observed a significant positive correlation of ALDH1A1 and a negative correlation of ALDH1A3 with TGFB1 in the PCa gene expression datasets TCGA PRAD (n = 493), MSKCC primary (n = 131), Broad/Cornell (n = 31), DKFZ (n = 118), and SMMU (n = 65) but not in the non-cancerous tissues (MSKCC cohort, n = 29) (Fig. 2C). This evidence concerns the gene TGFB1 and posterior cortical atrophy.