Anti-EIF2B Aab are found in 1–2% of patients with SSc and are associated with dcSSc, arthralgia and ILD.36 37 Anti-SNRPA are newly described, might be present in 11% of patients with SSc, are more often present in ATA-negative patients and are associated with PAH.38 This evidence concerns the gene SNRPA and pulmonary arterial hypertension.