ESR1 and breast cancer: Regarding BC subtypes (Table S11), genetically determined SSB consumption was consistently associated with an increased risk of estrogen receptor (ER)-negative BC (OR 5.69, 95% CI 1.22–26.63, P = 0.03), and was marginally associated with an increased risk of ER-positive BC (OR 3.07, 95% CI 0.94–9.98, P = 0.06).