PRL and Galactorrhea: While we did not have laboratory values for our cohort members, we evaluated ICD-9 diagnostic codes for endocrine conditions that are associated with alterations in prolactin and cortisol (i.e., hyperprolactinemia or galactorrhea not associated with childbirth); however, we did not include those conditions in the analysis due to low number of cases (i.e., < 5 among responders, Supplemental Table 1).