Other statistically significant M3AR pentamers targeted by AuAbs in acute PV were TLHNN (33% sera) and VHPTG (29% sera).The fact that each particular M3AR pentamer was not targeted by 100% of PV sera was not surprising, because we observed the same paradigm with the Dsg1 and Dsg3 sequences. Here, DSG1 is linked to acquired polycythemia vera.