ACHE and Alzheimer disease: Current approved treatments of AD by the Food and Drug Administration (FDA) include acetylcholinesterase (AChE) inhibitors (i.e. donepezil, galantamine, rivastigmine), N-methyl-d-aspartate (NMDA) receptor inhibitors (i.e. memantine), and anti-amyloid monoclonal antibodies (i.e. lecanemab and aducanumab).