For example, evidence suggests that inflammatory biomarkers like C-reactive protein (CRP), IL (interleukin)-6, IL-1b, TNF-a and D-dimer alongside cardiac biomarkers such as B-type natriuretic peptide (BNP) or its N-terminal fragment, NT-pro-BNP are all associated with cardioembolic stroke. The gene discussed is NPPB; the disease is cardioembolic stroke.