These data suggested the involvement of STAT3 in VEGFB-driven cardiac hypertrophy, although snRNA seq data from human or mouse hearts indicated that only VEGFB co-receptor NRP1/Nrp1 was expressed in cardiomyocytes, but not Nrp2, VEGFR1 (Flt1), VEGFR2 (Kdr), and VEGFR3 (Flt4) (see Supplementary material online, Figure S5; Figure 5H and I). The gene discussed is STAT3; the disease is cardiac hypertrophy.