In patients with low CD8+ T-cell infiltration at baseline (CD8 low), more patients had a low percentage of viable tumor cells (<20%) in the combination arm (6 of 19 patients with low baseline CD8+ T-cell infiltration achieving a low percentage of viable tumor cells) compared with patients with high CD8+ T-cell infiltration at baseline (2 of 11 patients). The gene discussed is CD8A; the disease is neoplasm.