It is important to highlight that Ins/Del variant at ACE gene and rs7903146 at TCF7L2 gene displayed BFDP values less than 0.2 at both the medium/low prior level (0.05 to 10-3) and the very low prior level (10-4 to 10-6), indicating their promising status as potential candidate genes for DKD. The gene discussed is ACE; the disease is diabetic kidney disease.