SOD1 and infection: Additionally, the ectopic overexpression of StSOS1-13 in Arabidopsis induced down-regulation of AtPR12. Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area.