Other than the peculiar type of dyschromatosis (Zhou et al., 2013; Zhong et al., 2019; Wu et al., 2020; Liu et al., 2021; Cao et al., 2021; Yang et al., 2023), the SASH1 mutations are also associated with another phenotype of skin pigmentation disorder: multiple lentigines (Shellman et al., 2015; Zhang et al., 2016; Wang et al., 2017; Araki et al., 2021; Kim et al., 2023). Here, SASH1 is linked to skin pigmentation disorder.