Among these parameters, the p SOFA score at 48 hours and lactate clearance at 24 hours were found to be statistically significant. Various sepsis markers such as CRP, procalcitonin, serum albumin, plasma lactate, and several mortality prognostic scores like the p SOFA score, pediatric risk of mortality III score (PRISM III), pediatric index of mortality 3 (PIM 3) score, and pediatric logistic organ dysfunction (PELOD) score are used to quantify the severity of the illness as well as estimate the probability of death [10,12-14]. This evidence concerns the gene CRP and Sepsis.