PTCH1 and leiomyoma: Notably, her unique clinical history involving medulloblastoma status post-resection and chemoradiation, followed by recurrent radiation-induced meningiomas, is an unusual incidental observation at this time and will require more cases with a molecular assessment to establish any genetic link. Medulloblastoma can be one of the manifestations of Gorlin syndrome (PTCH1 alterations), and previous reports have described these patients as developing leiomyomas in multiple visceral organs [18].