MAPT and dementia: Shorter durations of mainstream/sidestream smoke (1h/day x 1 month) induces lipid peroxides, DNA damage, and tau dysregulation (tau isomers, phosphotau) in the brain of neonatal mice (La Maestra et al., 2011), markers of neuropathology frequently observed in MCI and patients with dementia (Lovell and Markesbery, 2007; Simpson et al., 2016; Wirz et al., 2014).