It has been demonstrated that HO‐1 and NQO1 can exert protective effects in animal models of PF; for example, atractylenolide III inhibits BLM‐induced PF and oxidative stress via the Nrf2/NQO1/HO‐1 signaling pathway (Huai and Ding 2020). Here, HMOX1 is linked to pemphigus foliaceus.