CCR6 and hepatocellular carcinoma: Moreover, in vivo experiments evaluating subcutaneous tumor formation and lung metastasis demonstrated that treating HCC cells with CCL20-Ab or CCR6 knockdown can suppress the enhanced proliferative capacity (Figures 8A–D) and angiogenesis (Figures 8E, F) and increased number of lung metastases (Figure 8G, Supplementary Figure S7) induced by CM from HUVEC transfected with miR-183-5p mimics.