In these families, a deletion of approximately 22 kilobases (kb) that included exons 14 through 17 of CRIM1 was described in a family with microcornea, coloboma of the iris, choroid, retina, and optic disc, increased axial length, myopia, mild cornea plana, and a shallow anterior chamber (Toker et al., 2003; Beleggia et al., 2015). This evidence concerns the gene CRIM1 and Microcornea.