The GSEA for these samples indicated significant enrichment in pathways associated with Oxidative Stress Response, IL1 and Megakaryocytes In Obesity, Photodynamic Therapy-induced NFkb Survival Signaling, and TGF-beta Receptor Signaling In Skeletal Dysplasias (Figures 9J–N), with comprehensive details provided in Supplementary Table S12. This evidence concerns the gene IL1B and obesity due to melanocortin 4 receptor deficiency.