ZFP36L1 and autosomal dominant polycystic kidney disease: Confirming the uniqueness of the ECPKD phenotype to ADPKD, we found that the top DEGs enriched in ECPKD were detected at scant levels, or were not expressed, in our scRNA-seq reference atlas of human healthy and diseased kidney microvascular ECs (Fig. S2E), with the exception of the RNA-binding protein butyrate response factor 1 (ZFP36L1), which is required for normal vascularisation (Bell et al., 2006).