PKHD1 and autosomal recessive polycystic kidney disease: ECPKD was also enriched for PKHD1, which encodes fibrocystin, interacts with PKD1 (Olson et al., 2019) and is associated with autosomal recessive polycystic kidney disease (PKD) (log2FC=0.96, adjusted P=1.1×10−56), although PKD1 was not within the list of DEGs.