Inflammation is known to contribute to APAP induced injury, and Sema7a is known as an immunomodulator, so to start assessing the effect of Sema7a deficiency on inflammation during APAP-ALI, a panel of pro-inflammatory cytokines were quantified in the serum of Sema7a WT and Sema7a KO mice throughout the time course. The gene discussed is SEMA7A; the disease is acute respiratory distress syndrome.