Models that integrate PSA with miR-142-3p, miR-142-5p, and miR-223-3p achieved an AUC of 0.821 for PCa detection, while combinations incorporating miR-342-3p and miR-374b-5p distinguished higher-grade tumors with an AUC of 0.891, thereby improving diagnostic precision for PCa [153]. This evidence concerns the gene KLK3 and posterior cortical atrophy.