In contrast to these three main anti-apoptotic BCL2 proteins, the genes for the related anti-apoptotic BCL2 proteins Bfl1 (BCL2A1), BCL-w (BCL2L2) and BCL-B (BCL2L10) display little perturbation effects in cancer (mean Chronos Gene Dependency Scores −0.0454, −0.103 and 0.006, respectively). Here, BCL2 is linked to cancer.